ASCOGEN® is a unique formulation of purified RNA and purified nucleotides.Although not yet defined as essential nutrients, numerous scientifically confirmed trials demonstrated that purified nucleic acids must be regarded as a management tool to control stress and disease while maintaining or enhancing performance in agricultural livestock. Having been successfully used in all such applications, and more, they foster development, participate in cellular and molecular repair mechanisms and ensure unhindered cell proliferation without affecting growth, development or reproduction upon environmental, physical and pathogenic challenges.
Recommended dosagesGrand Parent Stocks: 500 g / tonne of feed Parent Stocks: 500 g / tonne of feedBreeder Hens: 500 g / tonne of feedLayers: 500 g / tonne of feed(Preferably this dosage should be maintained during the whole life starting from day-old)Broilers: 1000 g / tonne of feed for the first 10 days
Withdrawal periodNone
StabilityASCOGEN® is heat resistant and can be mixed with feed before pelleting or extruding
PackagingASCOGEN® is packed in 25kg polyethylene-lined white 5-ply paper bags
In this trial the performance of the ASCOGEN® group exceeds the control group. Throughout the whole trial, the broilers fed with ASCOGEN® fortified feed grew faster and achieved a higher final body weight at slaughter.
This trial was carried out with day old male Hubbart Chicks. The control group did not receive any ASCOGEN®. The second group received 500 g of ASCOGEN® / tonne of feed 8 days before and 8 days after vaccination against NDV. In the third group, the feeding of ASCOGEN® (same inclusion rate) was started at the day of vaccination for the next 16 days.
The course of specific antibody titres was monitored during the following weeks. It became obvious that aside from feeding with ASCOGEN®, the specific antibody titres were increased in both trial groups compared to the control. The effect was most pronounced in the group fed ASCOGEN® one week prior to vaccination.
Only farms with highly skilled management can achieve the performance target norms of the breeder companies.
In these trials, the flocks exceeded the norm of the breeder companies in terms of egg production % and laying persistency. The inclusion of ASCOGEN® in the diets enabled the farmer to accomplish the target norm of the breeding companies and fully utilise the genetic potential of the breed.
On Farm 1 the egg production % of the two different flocks have comparably responded to the feed (including ASCOGEN®) and management support. In weeks 29-31 a heat wave of 38°C caused a drop in egg production in both flocks but they recovered very quickly due to the influence of the ASCOGEN®.
On Farm 2 the trial is still ongoing. The egg production at this stage in both flocks continues to rise significantly and exceeds the breed norm by 6.6%. Moreover a reduction in mortality and an improvement in feed conversion ratio have been achieved.
The trial on Farm 3 is not yet finished. Both flocks respond and perform very closely to each other and are 6.6% above the breed production norms. The feed inputs and flock management are able to replicate a uniform performance response. Hatchability and feed efficiency continue to improve compared to the breed norms.Moreover, ASCOGEN® leads to reduction in mortality of the birds on this farm.
2006 SyriaThe role of nucleotides in the improvement and conversion rates in broiler chicken
2005 South AfricaPreliminary report
2005 SloveniaThe role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leucocytes
2005 PeruVaccination trial in chicken
2005 The NetherlandsSummary of Dutch case studies using ASCOGEN®
2003 United KingdomEffect of ASCOGEN® on the development of the intestinal structure in poultry
2003 SwitzerlandEffect of ASCOGEN® on growth of chicken
2003- 2004 The NetherlandsInfluence of ASCOGEN® on the formation of cuticle eggs
2002 SwitzerlandTrial in chicken mast
2001-2002 ItalyTrial with ASCOGEN® in broiler breeders
2001 ScotlandASCOGEN® trial and results on different organs
2000 IrelandBlood titre results for the ASCOGEN® trial
2000 HungaryPerformance trial
1999 VETERINARY FACULTY PAT.PERADIPerformance trial
1999 South KoreaDuck trial, egg production, laying rate
1999 POULTRY WORLD PUBLICATIONImproving productivity with alternatives
1999 CroatiaEffect of probiotic on production results of fattened chickens fed different quantities of protein
1999 United KingdomBreeder trial: costing calculated on production hatchability and ASCOGEN® cost
1998 United KingdomPerformance on their poultry
1997 SerbiaTrial with chicken. Effect of ASCOGEN® on the mast performance and the mortality of broilers
1996 FranceAntibody titres after vaccination against Aujeszky
1996 FranceBenefit in the prevention of coccidian in broilers
1996 United KingdomBreeding trial
1996 MalaysiaASCOGEN® in breeders, egg production
1995 / 1997 United KingdomAttwell farms develops the all natural turkey
1995 / 1996 FranceEffect on broiler breeders
1995 United KingdomLarge scale turkey trial
1995 2 X FARM 70 000 PM3 /ROSS 308Effect on the hatching rate of broiler breeders
1995 New ZealandBroiler trials
1994 United KingdomTurkey breeder trial
1993 BahrainAlmehza poultry farm performance
1993 ThailandEffect of ASCOGEN® in broiler, layer and African catfish rations
1993 / 1994 United KingdomBreeder trials
1992 RITTER ELHALT EMBRIOK ARANYAPerformance trial on layers
1992 FranceTrial with layers
1992 United KingdomHaemoglobin and erythrocyte determination
1992 / 1994 HungaryEffect of ASCOGEN® in geese especially in regard to production of down
1991 United KingdomTrial on broiler breeders, coccidiosis, IB variant, acute Marek
1991 / 1992 HungaryToxin neutralizing and immunostimulating effect of ASCOGEN® in breeding and duckling stocks
1991 / 1992 HungaryThe toxin neutralisation effect of ASCOGEN® in breeding stocks and young duck stocks
1990-1991 United KingdomTrial on broiler breeders
1990 SloveniaEffect of ASCOGEN® in parents
1990 HungaryEffect of ASCOGEN® on the action of the Fusarientoxin F-2 on gander
1989 SwitzerlandEffects on broiler fattening
1989 FIELD TRIAL J.P.WOODSBroiler fattening field trial
1989 / 1990 CroatiaSwollen head syndrome in hens and its control
1989 / 1990 EgyptASCOGEN® in laying hens different inclusion rate
1985 IndonesiaResults on nutritional trial with probioticum
1978 1979 CanadaEffect of ASCOGEN® on production, fertility and hatchability in turkey breeder flock
NO DATE UNITED FEED DR. MANEEASCOGEN®, toyocerin and chlortetracycline as feed additives in the starter of broiler diets: Effect on performance
NO DATE United KingdomDefence get a boost from feed additive (newspaper article): Egg production
NO DATE NO INDICATIONEffect of ASCOGEN® on layers (egg / bird / week)Effect of ASCOGEN® on cost of broilers (batch / bird)
NO DATE SloveniaEffectiveness of ASCOGEN® in comparison with antibiotic at turkey breeding
NO DATE HungaryLaying performance compared with ASCOGEN® concentration
NO DATE CoratiaEffect of probiotic ASCOGEN® on the growth performance of Japanese quail
NO DATE EgyptComparative studies on the growth promoting effect of ASCOGEN® and flavomycin in chickens
NO DATE EgyptStudies on the effect of ASCOGEN® on the immune response in chickens vaccinated with Newcastle Disease virus
NO DATE IndiaInfluence of ASCOGEN® ion broiler performance and antibody titres against Newcastle and infectious Bursal disease viruses
NO DATE ScotlandFinal report on the intestinal morphology of chickens receiving ASCOGEN® in a controlled blind study