Chemoforma Ltd.Chemoforma Ltd.

Trials in Poultry / List of trials

We recommend using 500 g of ASCOGEN® / tonne of feed for grand parents stock, parent stocks, breeder hens and layer. This dosage shall be maintained during the whole life. For broilers we recommend using 1000 g of ASCOGEN® / tonne of feed for the first 10 days.

ASCOGEN® an exceptional feed supplement

ASCOGEN® is a unique formulation of purified RNA and purified nucleotides.

Although not yet defined as essential nutrients, numerous scientifically confirmed trials demonstrated that purified nucleic acids must be regarded as a management tool to control stress and disease while maintaining or enhancing performance in agricultural livestock. Having been successfully used in all such applications, and more, they foster development, participate in cellular and molecular repair mechanisms and ensure unhindered cell proliferation without affecting growth, development or reproduction upon environmental, physical and pathogenic challenges.

Recommended dosages
Grand Parent Stocks:           500 g / tonne of feed
Parent Stocks:                     500 g / tonne of feed
Breeder Hens:                      500 g / tonne of feed
Layers:                                500 g / tonne of feed
(Preferably this dosage should be maintained during the whole life starting from day-old)
Broilers:                              1000 g / tonne of feed for the first 10 days

Withdrawal period
None

Stability
ASCOGEN® is heat resistant and can be mixed with feed before pelleting or extruding

Packaging
ASCOGEN® is packed in 25kg polyethylene-lined white 5-ply paper bags



Trials in Poultry

ASCOGEN® positively affects performance and intestinal development of broilers

Compared to the control animals, the development of the intestinal villi in the test group was accelerated. The average length of intestinal villi achieved in the control after 14 days was accomplished in the trial group at day 10. Similar results were obtained for the circumference of the villi. In general, the test animals completed the intestinal development 4 days earlier than the controls. This advance is retained throughout the life of the animals and is reflected in improved performance. Moreover, the intestinal defence mechanisms are established faster which, therefore, achieves an earlier protection from bacterial or viral infections as well as parasitic attacks.

 

In this trial the performance of the ASCOGEN® group exceeds the control group. Throughout the whole trial, the broilers fed with ASCOGEN® fortified feed grew faster and achieved a higher final body weight at slaughter.


ASCOGEN® improves the immunity

In a challenge experiment with birds from each trial groups, the protection against a virulent NDV was tested. 65% of the birds of the control group were protected from an infection with virulent NDV whereas the protection in the ASCOGEN® groups was 80% (ASCOGEN® after vaccination) or 90% (ASCOGEN® before and after vaccination) respectively.

This trial was carried out with day old male Hubbart Chicks. The control group did not receive any ASCOGEN®. The second group received 500 g of ASCOGEN® / tonne of feed 8 days before and 8 days after vaccination against NDV. In the third group, the feeding of ASCOGEN® (same inclusion rate) was started at the day of vaccination for the next 16 days.


 

The course of specific antibody titres was monitored during the following weeks. It became obvious that aside from feeding with ASCOGEN®, the specific antibody titres were increased in both trial groups compared to the control. The effect was most pronounced in the group fed ASCOGEN® one week prior to vaccination.


ASCOGEN® optimizes the genetic potential

Only farms with highly skilled management can achieve the performance target norms of the breeder companies.

In these trials, the flocks exceeded the norm of the breeder companies in terms of egg production % and laying persistency. The inclusion of ASCOGEN® in the diets enabled the farmer to accomplish the target norm of the breeding companies and fully utilise the genetic potential of the breed.

It needs to be noted that the weight of the birds on ASCOGEN® has to be carefully monitored and the feed adjusted to support the high egg production and prevent the birds from becoming overweight.



On Farm 1 the egg production % of the two different flocks have comparably responded to the feed (including ASCOGEN®) and management support. In weeks 29-31 a heat wave of 38°C caused a drop in egg production in both flocks but they recovered very quickly due to the influence of the ASCOGEN®.

The average feed usage per egg in this trial was 252 grams and the productivity exceeds the norm by 2.5 %.


On Farm 2 the trial is still ongoing. The egg production at this stage in both flocks continues to rise significantly and exceeds the breed norm by 6.6%. Moreover a reduction in mortality and an improvement in feed conversion ratio have been achieved.



The trial on Farm 3 is not yet finished. Both flocks respond and perform very closely to each other and are 6.6% above the breed production norms. The feed inputs and flock management are able to replicate a uniform performance response. Hatchability and feed efficiency continue to improve compared to the breed norms.

Moreover, ASCOGEN® leads to reduction in mortality of the birds on this farm.


List of trials

2006                 Syria
The role of nucleotides in the improvement and conversion rates in broiler chicken

2005                 South Africa
Preliminary report

2005                 Slovenia
The role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leucocytes

2005                 Peru
Vaccination trial in chicken

2005                 The Netherlands
Summary of Dutch case studies using ASCOGEN®

2003                 United Kingdom
Effect of ASCOGEN® on the development of the intestinal structure in poultry

2003                 Switzerland
Effect of ASCOGEN® on growth of chicken

2003- 2004        The Netherlands
Influence of ASCOGEN® on the formation of cuticle eggs

2002                 Switzerland
Trial in chicken mast

2001-2002         Italy
Trial with ASCOGEN® in broiler breeders

2001                 Scotland
ASCOGEN® trial and results on different organs

2000                 Ireland
Blood titre results for the ASCOGEN® trial

2000                 Hungary
Performance trial



1999                 VETERINARY FACULTY PAT.PERADI
Performance trial

1999                 South Korea
Duck trial, egg production, laying rate

1999                 POULTRY WORLD PUBLICATION
Improving productivity with alternatives

1999                 Croatia
Effect of probiotic on production results of fattened chickens fed different quantities of protein

1999                 United Kingdom
Breeder trial: costing calculated on production hatchability and ASCOGEN® cost

1998                 United Kingdom
Performance on their poultry

1997                 Serbia
Trial with chicken. Effect of ASCOGEN® on the mast performance and the mortality of broilers

1996                 France
Antibody titres after vaccination against Aujeszky

1996                 France
Benefit in the prevention of coccidian in broilers

1996                 United Kingdom
Breeding trial

1996                 Malaysia
ASCOGEN® in breeders, egg production

1995 / 1997      United Kingdom
Attwell farms develops the all natural turkey

1995 / 1996      France
Effect on broiler breeders



1995                 United Kingdom
Large scale turkey trial

1995                 2 X FARM 70 000 PM3 /ROSS 308
Effect on the hatching rate of broiler breeders

1995                 New Zealand
Broiler trials

1994                 United Kingdom
Turkey breeder trial

1993                 Bahrain
Almehza poultry farm performance

1993                 Thailand
Effect of ASCOGEN® in broiler, layer and African catfish rations

1993 / 1994      United Kingdom
Breeder trials

1992                 RITTER ELHALT EMBRIOK ARANYA
Performance trial on layers

1992                 France
Trial with layers

1992                 United Kingdom
Haemoglobin and erythrocyte determination

1992 / 1994      Hungary
Effect of ASCOGEN® in geese especially in regard to production of down

1991                 United Kingdom
Trial on broiler breeders, coccidiosis, IB variant, acute Marek

1991 / 1992      Hungary
Toxin neutralizing and immunostimulating effect of ASCOGEN® in breeding and duckling stocks

1991 / 1992      Hungary
The toxin neutralisation effect of ASCOGEN® in breeding stocks and young duck stocks

1990-1991         United Kingdom
Trial on broiler breeders



1990                 Slovenia
Effect of ASCOGEN® in parents

1990                 Hungary
Effect of ASCOGEN® on the action of the Fusarientoxin F-2 on gander

1989                 Switzerland
Effects on broiler fattening

1989                 FIELD TRIAL J.P.WOODS
Broiler fattening field trial

1989 / 1990      Croatia
Swollen head syndrome in hens and its control

1989 / 1990      Egypt
ASCOGEN® in laying hens different inclusion rate

1985                 Indonesia
Results on nutritional trial with probioticum

1978 1979         Canada
Effect of ASCOGEN® on production, fertility and hatchability in turkey breeder flock



NO DATE          UNITED FEED DR. MANEE
ASCOGEN®, toyocerin and chlortetracycline as feed additives in the starter of broiler diets: Effect on performance

NO DATE          United Kingdom
Defence get a boost from feed additive (newspaper article): Egg production

NO DATE          NO INDICATION
Effect of ASCOGEN® on layers (egg / bird / week)
Effect of
ASCOGEN® on cost of broilers (batch / bird)

NO DATE          Slovenia
Effectiveness of ASCOGEN® in comparison with antibiotic at turkey breeding

NO DATE          Hungary
Laying performance compared with ASCOGEN® concentration

NO DATE          Coratia
Effect of probiotic ASCOGEN® on the growth performance of Japanese quail

NO DATE          Egypt
Comparative studies on the growth promoting effect of ASCOGEN® and flavomycin in chickens

NO DATE          Egypt
Studies on the effect of ASCOGEN® on the immune response in chickens vaccinated with Newcastle Disease virus

NO DATE          India
Influence of ASCOGEN® ion broiler performance and antibody titres against Newcastle and infectious Bursal disease viruses

NO DATE          Scotland
Final report on the intestinal morphology of chickens receiving ASCOGEN® in a controlled blind study



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