Chemoforma Ltd.Chemoforma Ltd.

Trials in Pig / List of trials / Literature... ...some publications

We recommend using 2000 g of ASCOGEN® / tonne of feed before weaning and 1000 g of ASCOGEN® / tonne of feed until 40 days after weaning.

ASCOGEN® an exceptional feed supplement

ASCOGEN® is a specific formulation of yeast and yeast extract: PSB-Complex®.

Recommended dosages
Suckling piglets:     2000 g / tonne of feed
Weaners:               1000 g / tonne of feed until 40 days after weaning
Sows:                      500 g / tonne of feed during the whole year
or:
Lactating sows:    3 g per animal daily
Pregnant sows:     2 g per animal daily

Withdrawal period
None

Stability
ASCOGEN® is heat resistant and can be mixed with feed before pelleting or extruding

Packaging
ASCOGEN® is packed in 25kg polyethylene-lined white 5-ply paper bags

Trials in Pig

Effects of ASCOGEN® on performance and immune response in piglets


A dose-dependent increase in the daily weight gain became obvious in this trial in piglets. The effects of PSB-Complex® were more distinct when including 1000 g of ASCOGEN® / tonne of feed compared to 500 g. Moreover the morphological differences directly reflect the inclusion rate of ASCOGEN®. While the inclusion of 500 g / tonne of feed only affects the height of duodenal villi, an additional significant effect on the Jejunum is visible after inclusion of 1000 g / tonne of feed. Hypothetically, the active ingredients of ASCOGEN® are already exhausted in the Duodenum at 500 g / tonne of feed while further significantly improved Jejunum morphology is evident at inclusion of 1000 g of ASCOGEN® / tonne of feed.


An increase in specific Immunoglobulins was apparent in both trial groups with ASCOGEN® after stimulation of the immune system with LPS (lipopolysaccharide). The increase was more rapid and pronounced in the 1000 g of ASCOGEN® / tonne of feed group compared to the 500 g group. In both trial groups, the IgG’s were substantially increased. Even more pronounced was the effect on the specific Foot-and-Mouth-Disease-neutralizing antibodies after vaccination against FMD. Three weeks after vaccination, the antibody titre in the 1000 g of ASCOGEN® / tonne of feed group was still 4 times higher than the vaccinated control. 

This trial clearly demonstrates the positive effects of ASCOGEN® on the performance upon immunological challenges in piglets.

ASCOGEN® shows a dose-dependant increase in performance


Dose-dependent increase in average daily weight gain of piglets in a period of 68 days (89 days of age).


Dose-dependent final weight of piglets after 68 days. The inclusion of 2000 g of ASCOGEN® / tonne of feed achieved the highest weight in this experiment.



The feed conversion ratio showed a linear course in this experiment. The facilitated development of the intestinal tract with ASCOGEN® as well as the increase of the active intestinal surface area, lead to an improved FCR.

ASCOGEN® enhances the performance of piglets upon severe enteritic problems


Four different groups were used in this trial. The total length of the trial was 50 days, and feeding of 2000 g of ASCOGEN® / tonne of feed in group 2 started 7 days before weaning until weaning. The second trial group received ASCOGEN® for 25 days from weaning and the third trial group was fed with fortified feed for 32 days starting 7 days before weaning.


Performance data of piglets with severe enteritic problems. It was determined that feeding should start as early as possible in piglets in order to actively support the development of organs and the immune system. The best results however are achieved when feeding ASCOGEN® before and after weaning.


List of trials

2007 - China
ASCOGEN® trial report
(not yet available)

2007 - Germany
Performance results
(not yet available)

2007 - Spain
Dose-titration of ASCOGEN® in nursery pig diets
RESTRICTED AREA: Summary of trial available

2005 - Thailand
ASCOGEN®-piglets trial
(not yet available)

2005 - Ukraine
Benefits of ASCOGEN® on the performance of piglets
(not yet available)

2004 / 2005 - Slovenia
Effect of ASCOGEN® supplementation on lymphocyte DNA damage induced by dietary oxidative stress in pigs
RESTRICTED AREA: Summary of trial available

2004 - Brazil
Effect of ASCOGEN® on the partial replacement in piglet feed
RESTRICTED AREA: Summary of trial available

2004 - United Kingdom
ASCOGEN® with Mycoplasma vaccination
(not yet available)

2001 / 2002 - Austria
Use of ASCOGEN® in sows and piglets upon mycotoxins
RESTRICTED AREA: Summary of trial available

2001 / 2002 - Taiwan
Trial report for ASCOGEN® at the Tiger Mountain Farm
(not yet available)

2000 - Switzerland
Effect of ASCOGEN® on the performance of sows and piglets under the influence of ASCOGEN®
(not yet available)

1999 - Philippines
Evaluation of stillbirth, runts (below 900 gr), birth weight, litter size, mortality
RESTRICTED AREA: Summary of trial available

1997 - France
Results in feeding piglets
(not yet available)

1997 - Philippines
Efficacy of ASCOGEN® as biogenic performance enhancer in sow and piglets
RESTRICTED AREA: Summary of trial available

1997 -The Netherlands
Influenza and Aujesky virus
(not yet available)

1996 - Yugoslavia
Effect of ASCOGEN® on the fertility of sow
(not yet available)

1995 / 1996 - The Netherlands
Trial with 150 sows, experiences with ASCOGEN®
RESTRICTED AREA: Summary of trial available

1995 - Belgium
Trial with piglets, costs of medicines, feed conversion, mortality
(not yet available)

1995 - Philippines
Trial results on ASCOGEN®, farrowing rate, litter size, average birth weight, average weaning weight, number of piglets weaned, mortality
RESTRICTED AREA: Summary of trial available

1995 - Slovenia
Trial report of usage Farmatan in combination with ASCOGEN®: trial with piglets
(not yet available)

1994 / 1995 - Slovenia
Pig trial, weighing, feed consumption
(not yet available)

1994 / 1995 - The Netherlands
Trial in piglets, body weight, mortality, cost of medicines, feed conversion
(not yet available)

1994 - Hungary
The ASCOGEN® biological performance enhancers in pig production
RESTRICTED AREA: Summary of trial available

1994 - Hungary
Effect of ASCOGEN® on stress parameters in fattening pigs
(not yet available)

1994 - The Netherlands
Trial with piglets
RESTRICTED AREA: Summary of trial available

1993 - United Kingdom
Flatdeck feed trial
(not yet available)

1992 - Austria
Efficacy of ASCOGEN® on the capacity of reproduction on sows and on piglets breeding
(not yet available)


1992 - Austria
Examination of the effect of ASCOGEN® on the specific immune response and blood status on fattened pigs
(not yet available)

1992 - France
Trial with sows
RESTRICTED AREA: Summary of trial available

1992 - Switzerland
Demonstration of the effectiveness in a long-term trial
(not yet available)

1992 - The Netherlands
Effect on sows
(not yet available)

1992 - United Kingdom
Effects on white cell production in breeding pigs under disease stress condition
(not yet available)

1991 - Hungary
Effect of ASCOGEN® on the response of Zearalenon (F2-Toxin) on young sows
(not yet available)

1991 - Ireland
Effect on pigs
(not yet available)

1991 - Switzerland
Effect on pig fattening
(not yet available)

1990 / 1992 - Switzerland
Effect on pig fattening with ASCOGEN®
(not yet available)

1990 / 1991 - Austria
Effect on the immune response of pigs vaccinated with Parvovirus
RESTRICTED AREA: Summary of trial available

1989 - Australia
Effect on growth rate and feed conversion efficiency in weaner and grower pigs
(not yet available)

1989 - Malaysia
Trial on commercial pig farm, farm affected by swine Enzootic Pneumonia
(not yet available)

1988 - Germany
Effect of ASCOGEN® on the growth and intestinal flora of pigs
(not yet available)

1987 / 1988 - United Kingdom
Effects on pig reproduction and fattening
(not yet available)

1987 - USA
Effects of ASCOGEN® on faecal microbiology on young growing pigs and rats
RESTRICTED AREA: Summary of trial available

1982 / 1983 - Philippines
Performance of piglets from birth to weaning (26 days) initial litter (sows fed with ASCOGEN® in second part of the pregnancy) life cycle feeding trials of ASCOGEN®
RESTRICTED AREA: Summary of trial available

1978 - Tschech Republic
Comparison of ASCOGEN® with a negative and a positive control (Caradox) 
(not yet available)

1968 - Germany
Final report of test with ASCOGEN®
(not yet available)

Literature... ...some publications

Keywords: ASCOGEN®, Pig

Hoffmann K. and Barber J.
Can farmers grow pigs like mushrooms ?

Source: International Pig Topics / 2009
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Keywords: Pig, Performance

Tibble S., Koeppel P. and Van Kempen T.
ASCOGEN® supplementation enhances piglet performance

Source: ADSA-ASA Meeting, USA / 2006
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Keywords: ASCOGEN®, Pig, Stress

Salobir J. , Rezar V., Pajk T. and Levart A.
The effect of ASCOGEN® supplementation on oxidative stress induced by high dietary fat intake in pigs

Source: University of Ljubljana / 2003
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