Chemoforma Ltd.Chemoforma Ltd.

Trials in Fish / List of trials / Literature... ...some publications

We recommend using 2000 g to 2500 g of VANNAGEN® / tonne of feed for fish.

VANNAGEN® an exceptional feed supplement

VANNAGEN® is a specific formulation of yeast and yeast extract: PSB-Complex®.

Recommended dosage
2000-2500 g / tonne of feed

Withdrawal period
None

Stability
VANNAGEN® is heat resistant and can be mixed with feed before pelleting or extruding

Packaging
VANNAGEN® is packed in 25 kg polyethylene-lined white 5-ply paper bags

Trials in Fish

VANNAGEN® enhances the performance of Asian Sea Bass


The addition of 500 g of VANNAGEN® / tonne of trash fish fed to Asian Sea Bass for 96 days increased the performance of the fish remarkably. Besides an increase in the specific growth rate and daily weight gain, the feed conversion ratio was also improved.


VANNAGEN® improves the immunity of fish

The animals were exposed to a challenge with a virulent strain of Aeromonas which resulted in 98% mortality in the non-vaccinated control group. In the vaccinated control group 24% of the fish died, whereas in the VANNAGEN® group the mortality was reduced to 10%.


Antibody titres after intramuscular vaccination of Tilapia against Aeromonas hydrophila after inclusion of 500 g of VANNAGEN® / tonne of feed.


VANNAGEN® positively affects expression levels of genes involved in immune response in turbot


It was determined that IgM and RAG-1 gene expression were both significantly increased in the gill and spleen of fish fed the VANNAGEN®-fortified diet but decreased in the kidneys. Lysozyme expression was significantly decreased in the spleen and kidney of fish fed the VANNAGEN® diet without apparent effect to the gill.

Development of intestinal villi structures upon VANNAGEN®


Compared to the control animals, the length of the intestinal villi in the test group was increased after three weeks of feeding a VANNAGEN® fortified diet. This improves the protection from bacterial or viral infections as well as parasitic attacks. Moreover, the uptake of nutrients is facilitated due to the increased surface area of the intestinal structures.

List of trials

2006 - Thailand
An effect of VANNAGEN® in the Asian Sea Bass
(not yet available)

2005 - Malaysia
VANNAGEN® : The performance promoter
(not yet available)

2004 / 2005 - Thailand
Culture of Sea Bass (Lates Calcarifer Bloch) fed with diets containing different feed supplement
RESTRICTED AREA: Summary of trial available

2004 - Malaysia
Pond trial with VANNAGEN®
(not yet available)

2003 - Chile
Effect of a VANNAGEN®-enriched diet on the immune system, plasma levels and resistance to infectious pancreatic necrosis (IPN) in juvenile Rainbow Trout
(not yet available)

2003 - Middle East
Several studies and results
(not yet available)

2000 - Middle East
Effect of VANNAGEN® on the growth performance of African Catfish
RESTRICTED AREA: Summary of trial available

1999 - Norway
Better digestion, strengthened immune system
(not yet available)

1997 - Tschech Republic
Effect in farming success in Rainbow trout and wels
(not yet available)

1994 - Tschech Republic 
Effect of VANNAGEN® probiotics supplementation on the growth rate of Rainbow trout (Oncorhynchus Mykiss) under conditions of intensive culture
(not yet available)

1994 - Egypt
Effect of VANNAGEN® (Biogenic performance enhancer) on some pond fishes reared in Abbasa
(not yet available)

1994 - Egypt
The effect of VANNAGEN® on the immune response of Tilapia fish to Aeromonas Hydrophila vaccine
(not yet available)

1993 - Thailand
Effects of VANNAGEN® in broiler, layer and African Catfish rations
(not yet available)

1991 - Egypt
Effects on the growth rate of Tilapia fish
RESTRICTED AREA: Summary of trial available

1991 - Tschech Republic
Effect on growth and production in European Catfish
(not yet available)

Literature... ...some publications

Keywords: Fish

Hoffmann K.
Nucleic acids/nutrients shown essential

Source: Fish Farming International / 2008
>> Download <<

Keywords: Fish

Hoffmann K.
Essential nutrients in fish farming

Source: INFOFISH International / 2008
>> Download <<

Keywords: Fish, Immune system, Prebiotics, Probiotics

Hoffmann K.
Immunostimulation in aquaculture: What's the news?

Source: AQUA Culture Asia Pacific / 2007
>> Download <<

Keywords: Fish, VANNAGEN®

Yoonaisil T. and Hertrampf J.W.
An effect of VANNAGEN® in the Asian Seabass

Source: AQUA Culture Asia Pacific / 2006
>> Download <<

Keywords: Fish, Disease, Stress

Burrells C.
VANNAGEN® aid dietary louse control

Source: Fish Farmer / 2001
>> Download <<

Keywords: Fish, Immune system

Burrells C. and Williams P.
The EWOS research programme on immunostimulants

Source: EWOS Perspective / 2001
>> Download <<

Keywords: Fish, Immune system

Myhr E.
Strong, healthy and growing fast

Source: EWOS Perspective / 2001
>> Download <<

Keywords: Fish, Performance, Development

Burrells C.
Advice on Vextra booster feed

Source: Aqua / 1999
>> Download <<

Keywords: Fish, Immune system

Burrells C.
Better digestion, strengthened immune system

Source: EWOS Perspective / 1999
>> Download <<

Keywords: Fish, Nutrition

Horne M.
New approaches in koi health

Source: Koi Health Quarterly / 1997
>> Download <<

Keywords: Fish, Nutrition

Schel C. L.
Nutrition for dummies

Source: Hofstra University / 1996
>> Download <<

Keywords: Fish, Poultry, Performance

Thongwittaya N. Pipoppinyo S. and Puranapong P.
Effects of ASCOGEN in broiler, layer and African Catfish rations

Source: SIAM Qualified produces Ltd. Partnership / 1992
>> Download <<

Keywords: Fish, VANNAGEN®, Performance

Ramadan A, Atef M. and Afifi N.A.
Effect of the biogenic performance enhancer (VANNAGEN®) on growth rate of tilapia fish

Source: Acta Veterinaria Scandinavia / 1991
>> Download <<

Keywords: Fish, Performance

Ramadan A., Atef M. and Afifi N. A.
Effect of VANNAGEN® on growth rate of tilapia fish

Source: Cairo University / 1991
>> Download <<